Miss Wilcox

Biology I

Natural Selection – June 19, 2007

Approximate time: 50 minutes

Objectives: TSW

1.Summarize main concepts in DNA technology (extraction and gel electrophoresis, recombinant DNA, transgenic organisms, reproductive cloning). 5c

2.Analyze the applications of DNA technology (forensics, medicine, agriculture). 5c

3.Apply acquired knowledge of DNA technology to invent and explain an original transgenic organism. 5c

Materials:

White board, markers, technology worksheet, pencils, transparencies, vis-a-vis pens, construction paper

Warm-up:

1.Name the 3 types of gene mutations.

2.Name the 4 types of chromosomal mutations.

3.What is a karyotype?

Set: (review, objectives, involve, relevance)

Say, “Who has watched a forensics show on TV? How do they sometimes identify a suspect as being   guilty of a crime? Comparing their DNA to a sample at the scene...each person's DNA is unique, and so this provides scientific evidence of their involvement in the crime.

Say, “We have been learning about molecular genetics, the study of DNA molecules and changes in DNA. In the past 30 years, molecular genetics has developed into the field of genetic engineering, which involves making changes in an organism's DNA. Yesterday, we identified the kinds of changes that can happen to DNA in a cell. Today, we will learn about how geneticists study DNA and summarize and main concepts in DNA technology and their applications.”

(5)

Procedures:

1.Give notes on DNA uniqueness, DNA extraction, gel electrophoresis, DNA fingerprinting, recombinant DNA, transformation, plasmids, transgenic, reproductive cloning. (10)

2.Assign discussion groups on applications of technology, ethics. Ask how could DNA technology by applied in the fields of forensics, medicine, and agriculture? What are some concerns of using biotechnology? (6)

3.Have students make transgenic organism using construction paper and pencils. Ask what is   the organism into which you are placing foreign genes? The gene for what trait is being added to the organism's DNA? From where is it coming (what organism)? What is the name of your transgenic organism? Why did you choose the gene you did (what benefit does it afford the transgenic organism)?  (15)

4.Have students share their organisms by presenting to the class. (9)

5.If time permits, have students start worksheet, finish for homework.

Closure: (restate, review, involve, preview)

Say, “Our objectives today were to summarize main concepts in DNA technology such as extraction and gel electrophoresis, recombinant DNA, and reproductive cloning, to analyze the applications of DNA technology (forensics, medicine, agriculture), and to apply what we learned about DNA technology to invent and explain an original transgenic organism. What technology did we discuss? How are these technologies applied? Tomorrow, we will begin with a brief review of all of molecular genetics and technology before we have a test on the material. Remember to study!”  (5)

Assessment:

    Informal: TTW listen to discussion on applications of technologies and to the     presentations on transgenic organisms.

    Formal: TTW grade the worksheet on technology checking for understanding of     technology vocabulary, processes, and applications. The grade will be     recorded in the grade book.